High Mutation Frequency Induced by Hybridization

Genetics: A. H. Sturtevant High Mutation Frequency Induced by Hybridization

High-frequency oscillations of Newton's constant induced by inflation.

We examine the possibility that an epoch of inflationary expansion induces high-frequency oscillations of Newton’s constant, G. The effect occurs because inflation can shift the expectation value of a non-minimally coupled, BransDicke-like field away from the minimum of its effective potential. At some time after inflation ends, the field begins to oscillate, resulting in periodic variations in...

High frequency repeat-induced point mutation (RIP) is not associated with efficient recombination in Neurospora.

Duplicated DNA sequences in Neurospora crassa are efficiently detected and mutated during the sexual cycle by a process named repeat-induced point mutation (RIP). Linked, direct duplications have previously been shown to undergo both RIP and deletion at high frequency during premeiosis, suggesting a relationship between RIP and homologous recombination. We have investigated the relationship bet...

ENU induced single mutation locus on chr 16 leads to high-frequency hearing loss in mice.

The hallmark of age-related (presbycusis) and noise-induced hearing loss is high-frequency (> 20 kHz) hearing loss. Through a collaborative study with TMGC (Tennessee Mouse Genome Consortium), seventeen ENU-induced mouse mutation strains with high-frequency hearing loss have been identified, but affected genes are yet identified. As a first step in identifying the gene/s underlying the ENU muta...

Modification by manganous chloride of the frequency of mutation induced by nitrogen mustard.

HE fact that a posttreatment can abolish the mutations induced by a mutaTgenic agent can furnish a tool for the study of the metabolic conditions that are necessary for the completion of processes that begin with the mutagenic treatment and lead finally to mutation (WITKIN 1956; DOUDNEY and HAAS 1958, 1960). Different agents can produce a decrease in the mutation frequency after UV treatment: v...